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Item No	Product Name	Product Description	Inquiry

R-SX-011	KU-55933CAS587871-26-9	KU-55933 (ATM Kinase Inhibitor) is a potent and specific ATM inhibitor with IC50/Ki of 12.9 nM/2.2 nM in cell-free assays, and is highly selective for ATM as compared to DNA-PK, PI3K/PI4K, ATR and mTOR.西安瑞禧生物提供各種抑制劑材料。	查看詳細(xì)
R-SX-012	TWS11CAS601514-19-6	TWS119 is a GSK-3β inhibitor with IC50 of 30 nM in a cell-free assay; capable of inducing neuronal differentiation and may be useful to stem cell biology.西安瑞禧生物提供各種抑制劑材料。	查看詳細(xì)
R-SX-013	NVPBKM120CAS944396-07-0	BKM120 (NVP-BKM120, Buparlisib) is a selective PI3K inhibitor of p110α/β/δ/γ with IC50 of 52 nM/166 nM/116 nM/262 nM in cell-free assays, respectively. Reduced potency against VPS34, mTOR, DNAPK, with little activity to PI4Kβ. Phase 2.西安瑞禧生物提供各種抑制劑材料。	查看詳細(xì)
R-SX-014	Torkinib;PP242CAS1092351-67-1	Torkinib (PP 242) 是選擇性，ATP競(jìng)爭(zhēng)型的 mTOR 抑制劑，IC50 為 8 nM。PP242 抑制 mTORC1 和 mTORC2 的 IC50 分別為 30 nM 和 58 nM。西安瑞禧生物提供各種抑制劑材料。	查看詳細(xì)
R-SX-015	XL765CAS1123889-87-1	Voxtalisib (SAR245409, XL765) is a dual inhibitor of mTOR/PI3K, mostly for p110γ with IC50 of 9 nM; also inhibits DNA-PK and mTOR. Phase 1/2.西安瑞禧生物提供各種抑制劑材料。	查看詳細(xì)
R-SX-016	PI103 Free baseCAS371935-79-4	PI-103 is a multi-targeted PI3K inhibitor for p110α/β/δ/γ with IC50 of 2 nM/3 nM/3 nM/15 nM in cell-free assays, less potent to mTOR/DNA-PK with IC50 of 30 nM/23 nM.西安瑞禧生物提供各種抑制劑材料。	查看詳細(xì)
R-SX-017	YM201636CAS371942-69-7	YM201636 is a selective PIKfyve inhibitor with IC50 of 33 nM, less potent to p110α and insensitive to Fabl (yeast orthologue).西安瑞禧生物提供各種抑制劑材料。	查看詳細(xì)
R-SX-018	Torin2CAS1223001-51-1	Torin 2 是一種 mTOR 抑制劑，抑制細(xì)胞內(nèi) mTOR 活性，EC50 為 0.25 nM，比作用于 PI3K (EC50: 200 nM) 選擇性高 800 倍。體外酶實(shí)驗(yàn)中，Torin 2 還抑制 DNA-PK，IC50 為 0.5 nM。Torin 2 抑制 mTORC1 和 mTORC2。西安瑞禧生物提供各種抑制劑材料。	查看詳細(xì)
R-SX-019	BYL719CAS1217486-61-7	Alpelisib (BYL719) is a potent and selective PI3Kα inhibitor with IC50 of 5 nM in a cell-free assay, and minimal effect on PI3Kβ/γ/δ. Phase 2.西安瑞禧生物提供各種抑制劑材料。	查看詳細(xì)
R-SX-020	GDC0941; PictilisibCAS957054-33-0	Pictilisib (GDC-0941) is a potent inhibitor of PI3Kα/δ with IC50 of 3 nM in cell-free assays, with modest selectivity against p110β (11-fold) and p110γ (25-fold). Phase 2.西安瑞禧生物提供各種抑制劑材料。	查看詳細(xì)
R-SX-021	Bikinin; AbrasinCAS188011-69-0	Bikinin 是一種非甾體類的，植物性 GSK-3/Shaggy-like kinases 的 ATP 競(jìng)爭(zhēng)性抑制劑，可激活 BR 信號(hào)通路,西安瑞禧生物提供各種抑制劑材料。	查看詳細(xì)
R-SX-022	GDC0941CAS957054-30-7	Pictilisib (GDC-0941) is a potent inhibitor of PI3Kα/δ with IC50 of 3 nM in cell-free assays, with modest selectivity against p110β (11-fold) and p110γ (25-fold). Phase 2.西安瑞禧生物提供各種抑制劑材料。	查看詳細(xì)

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